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Neurons with amyloid plaques.iStock/selvanegraHealthUntangling the connectionStephanie M. McPhersonHMS CommunicationsMarch 15, 20194 min readInsulin signaling failures in the brain linked to Alzheimer s diseaseScientists continue to find evidence linking Type 2 diabetes <a href=https://www.asicsgel.de>asics</a> with Alzheimer s disease, the most common form of dementia and the seventh-leading cause of death in the United States. However, little is understood about the m <a href=https://www.stanley-cup.com.de>stanley cup becher</a> echanism by which the two are connected.Now, Harvard Medical School HMS researchers at聽Joslin Diabetes Center聽have demonstrated that impaired insulin signaling in the brain negative <a href=https://www.stanley-cup.com.de>stanley shop</a> ly affects cognition, mood, and metabolism, all components of Alzheimer s disease.In the study, reported in the聽Proceedings of the National Academy of Sciences, the researchers聽developed a novel mouse model in which they blocked the expression in the brain of both insulin receptors and the closely related insulin-like growth factor IGF1 receptors to two regions critical for learni |